FIGURE 3.
Huaier regulates PI3K/AKT/HIF‐1α pathway. Huaier (4 and 8 mg/mL) was used to treat lung cancer A549 cells. (A‐B) Huaier obviously decreased the protein expression of p‐AKT and HIF‐1α. PI3K: phosphatidylinositol 3‐kinase; HIF‐1α, hypoxia‐inducible factor‐1. *Compared with control group, P < .05; #Compared with 4 mg/mL group, P < .05