FIGURE 5.

Piezo1 could promote cell migration via up‐regulation of HIF‐1α in GC cell. A, B, Representative images of SNU‐1 and HGC‐27 two GC cells stably transfected with HIF‐1α and Piezo1 knockdown. C, D, Western blot was used to assess the transfection efficiency of HIF‐1α knockdown in GC cells. E‐H, Transwell assay was performed to detect the migrant ability of GC cells after treatment with si‐Piezo1, Yoda1 or si‐Piezo1 + Yoda1. I‐L, Wound healing assay was used to measure the wound distance for GC cells transfected with si‐Piezo1, Yoda1 or si‐Piezo1 + Yoda1. *P < .05; **P < .01; ****P < .0001