Figure 1.

Pathological changes and NF‐κΒ expression in two murine models of CP. A, B, Schematic model for CP. C–F, H&E and Masson's trichrome staining in the pancreas of the CP models induced by cerulein (C, D) or l‐arginine (E, F) at weeks 2, 4 and 6 (original magnification: 200×). Pancreatic pathological score involving oedema, inflammation, atrophy, necrosis and fibrosis (n = 10). The CP group vs the control group: ^** P < .01, ^*** P < .001. G, H, Western blotting of NF‐κBp65 expression in both murine CP models (representative blot, n = 3). The relative protein abundance was quantified through densitometry analysis. The CP group vs the control group: ^* P < .05, ^** P < .01