Table 1.
Univariate Cox regression analysis of the association of the TFAP4 level with patients’ survival
| Cancer | OS | DSS | DFI | PFI | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HR | HR(95% CI) | P‐value | HR | HR(95% CI) | P‐value | HR | HR(95% CI) | P‐value | HR | HR(95% CI) | P‐value | |
| ACC | 2.781 | 1.002–7.718 | .049 | 2.384 | 0.81–7.019 | .115 | 10.115 | 1.863–54.935 | .007 | 2.970 | 1.297–6.800 | .010 |
| BLCA | 0.855 | 0.617–1.185 | .347 | 0.863 | 0.597–1.248 | .433 | 0.969 | 0.464–2.027 | .934 | 1.001 | 0.736–1.363 | .993 |
| BRCA | 0.805 | 0.570–1.136 | .216 | 0.688 | 0.450–1.052 | .084 | 1.314 | 0.867–1.992 | .197 | 0.881 | 0.641–1.210 | .433 |
| CESC | 0.961 | 0.561–1.647 | .885 | 1.057 | 0.580–1.925 | .856 | 1.228 | 0.515–2.923 | .643 | 1.222 | 0.721–2.072 | .456 |
| CHOL | 1.759 | 0.487–6.347 | .389 | 0.999 | 0.452–2.211 | .999 | 1.053 | 0.398–2.784 | .918 | 0.888 | 0.426–1.853 | .752 |
| COAD | 1.165 | 0.721–1.883 | .533 | 0.928 | 0.582–1.478 | .752 | 1.536 | 0.663–3.559 | .317 | 0.953 | 0.680–1.335 | .780 |
| DLBC | 0.708 | 0.153–3.278 | .659 | 0.957 | 0.119–7.703 | .967 | 0.846 | 0.019–38.286 | .932 | 2.029 | 0.545–7.556 | .291 |
| ESCA | 0.777 | 0.453–1.333 | .359 | 0.743 | 0.391–1.410 | .363 | 0.944 | 0.421–2.116 | .888 | 1.073 | 0.687–1.676 | .756 |
| GBM | 0.792 | 0.497–1.262 | .327 | 0.822 | 0.479–1.411 | .477 | / | / | / | 0.494 | 0.303–0.803 | .004 |
| HNSC | 0.892 | 0.688–1.157 | .388 | 0.771 | 0.568–1.048 | .096 | 0.679 | 0.323–1.427 | .307 | 0.862 | 0.668–1.112 | .252 |
| KICH | 0.780 | 0.152–4.014 | .767 | 0.417 | 0.079–2.211 | .304 | 0.188 | 0.014–2.430 | .200 | 0.394 | 0.102–1.528 | .178 |
| KIRC | 2.453 | 1.622–3.711 | <.001 | 2.935 | 1.839–4.686 | <.001 | 0.834 | 0.248–2.803 | .769 | 2.295 | 1.556–3.386 | <.001 |
| KIRP | 4.954 | 2.201–11.155 | <.001 | 4.706 | 1.943–11.397 | .001 | 1.816 | 0.573–5.758 | .311 | 2.083 | 1.066–4.068 | .032 |
| LAML | 0.681 | 0.375–1.236 | .207 | / | / | / | / | / | / | / | / | / |
| LGG | 0.560 | 0.365–0.860 | .008 | 0.541 | 0.338–0.864 | .010 | 1.235 | 0.398–3.831 | .715 | 0.553 | 0.389–0.785 | .001 |
| LIHC | 2.469 | 1.559–3.910 | <.001 | 1.893 | 1.110–3.228 | .019 | 1.872 | 1.276–2.747 | .001 | 1.941 | 1.376–2.740 | <.001 |
| LUAD | 0.864 | 0.603–1.238 | .425 | 0.814 | 0.559–1.186 | .284 | 1.360 | 0.885–2.090 | .161 | 0.963 | 0.724–1.280 | .793 |
| LUSC | 0.848 | 0.641–1.123 | .250 | 0.615 | 0.432–0.874 | .007 | 0.872 | 0.566–1.344 | .536 | 0.721 | 0.551–0.944 | .017 |
| MESO | 1.379 | 0.774–2.456 | .275 | 1.778 | 0.791–4.000 | .164 | 0.935 | 0.108–8.081 | .951 | 1.500 | 0.795–2.832 | .211 |
| OV | 1.164 | 0.906–1.495 | .235 | 1.167 | 0.893–1.525 | .259 | 1.008 | 0.730–1.393 | .960 | 0.956 | 0.749–1.220 | .715 |
| PAAD | 1.391 | 0.770–2.515 | .274 | 1.109 | 0.568–2.163 | .762 | 0.900 | 0.233–3.472 | .878 | 1.074 | 0.624–1.846 | .797 |
| PCPG | 0.755 | 0.077–7.434 | .810 | 1.421 | 0.112–18.038 | .786 | 0.165 | 0.005–4.975 | .300 | 0.719 | 0.183–2.826 | .636 |
| PRAD | 1.428 | 0.325–6.268 | .637 | 4.347 | 0.515–36.663 | .177 | 4.107 | 1.728–9.761 | .001 | 2.273 | 1.383–3.738 | .001 |
| READ | 0.328 | 0.138–0.779 | .012 | 0.444 | 0.175–1.126 | .087 | 0.868 | 0.196–3.844 | .852 | 0.795 | 0.418–1.510 | .483 |
| SARC | 1.478 | 0.999–2.188 | .051 | 1.525 | 0.999–2.329 | .051 | 1.140 | 0.727–1.787 | .568 | 1.131 | 0.813–1.573 | .466 |
| SKCM | 1.415 | 1.043–1.920 | .026 | 1.484 | 1.068–2.060 | .019 | / | / | / | 1.093 | 0.841–1.419 | .506 |
| STAD | 0.698 | 0.491–0.993 | .046 | 0.752 | 0.489–1.156 | .193 | 0.714 | 0.381–1.337 | .293 | 0.820 | 0.574–1.171 | .275 |
| TGCT | 1.147 | 0.046–28.897 | .934 | 2.056 | 0.074–57.100 | .671 | 1.670 | 0.586–4.760 | .337 | 1.037 | 0.406–2.651 | .939 |
| THCA | 2.287 | 0.552–9.475 | .254 | 8.027 | 1.536–41.948 | .014 | 1.031 | 0.351–3.027 | .955 | 2.789 | 1.393–5.583 | .004 |
| THYM | 0.173 | 0.025–1.202 | .076 | 5.807 | 0.129–261.867 | .365 | / | / | / | 0.671 | 0.180–2.500 | .552 |
| UCEC | 1.346 | 0.854–2.120 | .201 | 1.608 | 0.927–2.790 | .091 | 2.056 | 1.166–3.626 | .013 | 1.681 | 1.146–2.466 | .008 |
| UCS | 0.684 | 0.298–1.570 | .370 | 0.879 | 0.378–2.043 | .764 | 1.148 | 0.253–5.217 | .858 | 0.924 | 0.433–1.971 | .837 |
| UVM | 0.156 | 0.039–0.623 | .009 | 0.119 | 0.027–0.513 | .004 | / | / | / | 0.299 | 0.085–1.055 | .061 |
Abbreviations: DSS, disease‐specific survival; DFI, disease‐free interval; OS, overall survival; PFI, progression‐free interval.