TABLE 1.

The protective effect of carveol on liver functional enzymes: APAP augmented the serum level of LFTs and attenuated high-density lipoprotein (HDL) level, while carveol, with respect to APAP, mitigated LFT levels and increased HDL levels.

Treatment	ALT (U/L)	AST (U/L)	TP (g/dl)	TB (mg/dl)	ALP (U/L)	Albumin (g/dl)	LDL (mg/dl)	HDL (mg/dl)
Saline	59 ± 8.71	106 ± 13.89	7.8 ± 0.30	0.33 ± 0.18	98.66 ± 15.53	4.93 ± 0.65	39 ± 5.56	78.66 ± 8.02
APAP 400 mg/kg	194.66 ± 6.02***	276.66 ± 27.02***	3.53 ± 0.40***	2.16 ± 0.30***	220.33 ± 49.44***	2.23 ± 0.30***	102.66 ± 13.05***	37.66 ± 2.51***
APAP + Carveol 5 mg/kg	164.66 ± 10.69	269.33 ± 81.5	5.7 ± 0.45##	1.23 ± .37##	177 ± 11.78	3.5 ± 36	78.66 ± 17.4	41.66 ± 3.05
APAP + Carveol 10 mg/kg	148.33 ± 11.37#	258.66 ± 36.67	5.53 ± 1.19##	1.03 ± .20##	136.66 ± 3.05##	4.23 ± .41#	64 ± 21#	52.66 ± 6.5#
APAP + Carveol 15 mg/kg	95.33 ± 7.37###	172.33 ± 14.7##	6.6 ± 0.55###	0.525 ± 0.03###	122.66 ± 8.50###	4.5 ± 0.36##	65.66 ± 17.67##	64.66 ± 7.76##
APAP + Silymarin 50 mg/kg	81.33 ± 8.50###	138.66 ± 14.22##	6.16 ± 0.40###	0.67 ± 0.29###	130 ± 16.70###	5.93 ± 0.85##	51.33 ± 9.29##	52.33 ± 2.08#

The data are presented as means ± SEM and were analyzed using one-way ANOVA with n = 7/group. The symbols ∗∗∗ and ### represent p < 0.001 and the symbol ## represents p < 0.01 values of significant differences. The samples were processed from cohort 1.