TABLE 2.
Effect of carveol on oxidative enzymes.
Treatment | GSH (μmol/mg protein) | GST (nmoles of CDNS conjugated/min/mg protein) | TBARS (nmoles Tbras/min/mg protien) |
---|---|---|---|
Saline | 74.88 ± 13.78 | 25.42 ± 1.30 | 79.32 ± 0.70 |
APAP 400 mg/kg | 6.30 ± 4.97*** | 1.78 ± 1.50*** | 215.58 ± 5.82*** |
APA + Carveol 5 mg/kg | 44.4 ± 9.26# | 4.67 ± 0.91 | 192.54 ± 2.80 |
APA + Carveol 10 mg/kg | 54.49 ± 9.98## | 8.83 ± 1.62# | 167.78 ± 2.164# |
APA + Carveol 15 mg/kg | 62.29 ± 18.82### | 14.2 ± 1.43## | 131.74 ± 0.64## |
APAP + Silymarin 50 mg/kg | 66.68 ± 11.45### | 18.20 ± 2.31## | 115.83 ± 2.164## |
The symbols ∗∗∗ and ### represent p < 0.001, while the symbol ## or # represents p < 0.01 and p < 0.05, n = 7/group. The data are expressed as mean ± SEM and were analyzed using one-way ANOVA followed by Tukey’s multiple comparison test. The samples were processed from cohort 1.