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Effect of carveol on histopathological scoring.
| Groups | Hepatocytes necrosis | Inflammatory cells infiltration | Fatty degeneration/vacuolization |
|---|---|---|---|
| Saline | — | — | — |
| APAP 400 mg/kg | +++ | +++ | +++ |
| APA + Carveol 5 mg/kg | +++ | ++ | ++ |
| APA + Carveol 10 mg/kg | + | + | + |
| APA + Carveol 15 mg/kg | — | — | ± |
| APAP + Silymarin 50 mg/kg | — | — | ± |
+++ significant, ++ high, + moderate, —nil.
