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. 2020 Dec 9;4(2):e1320. doi: 10.1002/cnr2.1320

TABLE 1.

Modification in practice of rectal cancer

S. No. Treatment modality Modification strategy
1. Radiotherapy
  • Intermediate risk: SCRT where needed

  • Locally advanced: SCRT followed by chemotherapy

  • Avoid post‐operative radiotherapy. Indicated only in select T4, margin positive and N2 disease

  • Wait and watch approach where feasible

2. Surgery Delay in surgery following radiation:
  • 4 to 6 weeks after SCRT

  • ≥12 weeks after LCRT or SCRT with chemotherapy

3. Chemotherapy
  • Avoid adjuvant chemotherapy

  • Oral capecitabine‐based chemotherapy in high‐risk cases

  • Omit addition of oxaliplatin

  • Total neoadjuvant approach

  • Avoid bolus 5FU

Abbreviations: LCRT, long‐course radiotherapy; SCRT, short‐course radiotherapy.