Table 1.
Summary of positive results for the negative control samples obtained by ELISA and IF
Negative cohort | IF IgM | IF IgA | IF IgG | ELISA IgA | ELISA IgG |
---|---|---|---|---|---|
B (n = 105) | 1 | 0 | 1 | 7 | 5 |
A (n = 34) | 0 | 0 | 1 | 3 | 1 |
Z (n = 22) | 0 | 0 | 0 | 2 | 0 |
E (n = 57) | 0 | 0 | 0 | 11 | 1 |
Total (n = 218) | 1 (0.5%) | 0 (0.0%) | 2 (0.9%) | 23a (10.6%) | 7a (3.2%) |
The classification of positive or borderline results in ELISA followed the definition of the test manufacturer. The classification in IF is described in materials and methods. Positive IgA and IgG ELISA readings were derived from the same sample. Cohort B = healthy donors, cohort A = patients that tested positive for ccCoV (all four types of ccCoV represented), cohort Z = patients with diagnosed Mycoplasma pneumoniae, cohort E = patient with diagnosed EBV or CMV infection.
a – borderline values were considered positive.