TABLE 3.
Comparison of primary and secondary clinical outcomes in solid organ transplant and non‐transplant controls in the coarsened exact matched cohort
| Clinical outcomes a | SOT group (n = 128) | Non‐SOT group (n = 3907) | p‐value |
|---|---|---|---|
| Primary outcome | |||
| Death | 28 (21.9%) | 580.92 (14.9%) | .04 |
| Kidney | 23/28 (82.1%) | NA | NA |
| Kidney‐liver | 2/28 (7.1%) | NA | NA |
| Liver | 2/28 (7.1%) | NA | NA |
| Heart | 1/28 (3.6%) | NA | NA |
| Key secondary outcomes | |||
| AKI | 43 (33.6%) | 789.3 (20.2%) | <.01 |
| ARDS | 34 (26.6%) | 938.26 (24%) | .58 |
| Required vasopressor | 30 (23.4%) | 630.72 (16.1%) | .04 |
| Received ICU care | 50 (39.1%) | 1318.25 (33.7%) | .25 |
| Median length of stay (IQR) – d | |||
| Discharged | 4 [2, 10] | 5 [2, 10] | .67 |
| Expired | 9 [4, 27] | 13 [6, 20] | .75 |
| Median time from infection to outcome (IQR)—d | 7 [3, 13] | 7 [3, 14] | .77 |
| Level of respiratory support at most severe | |||
| No supplemental oxygen | 26 (20.3%) | 613.79 (15.7%) | .20 |
| Received low‐flow supplemental oxygen | 44 (34.4%) | 1544.5 (39.5%) | .28 |
| Received non‐invasive ventilation or high‐flow oxygen devices | 16 (12.5%) | 830.66 (21.3%) | .02 |
| Received invasive mechanical ventilation | 38 (29.7%) | 792.57 (20.3%) | .01 |
| Received ECMO | 0 (0%) | 10.1 (0.3%) | 1.00 |
| No evidence of respiratory support | 0 (0%) | 10.1 (0.3%) | 1.00 |
Intensive care and vasopressors are considered received if the patient received intensive care or vasopressor support, respectively, at any point in the hospital stay. Level of respiratory support at most severe is defined as the highest daily level reached during hospitalization on the modified 5‐point scale.
Abbreviations: AKI, acute kidney injury; ARDS, acute respiratory distress syndrome; ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit.
a
Data are presented as counts and percentages unless otherwise noted.