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. 2021 Jan 14;121(3):1746–1803. doi: 10.1021/acs.chemrev.0c00779

Figure 6.

Figure 6

Time-dependent in vivo breast tumor imaging with etchable ZHS-QDs. Normal mice and mice bearing orthotopic MCF10CA1a human breast tumors received an intravenous injection of iRGD, CRGDC, or PBS before intravenous ZHS-QD injection. Ag-TS or PBS was given intraperitoneally. n = 4 per group. (a) The mice were anesthetized and imaged from the ventral side with a Li-Cor Pearl imager under 800 nm channel at the indicated time points. Arrows, tumors. (b) NIR signals in the tumor per unit area plotted against time. (c) Time-dependent changes of CI in the tumor area. Statistics, two-way analysis of variance; error bars, SEM; ns, not significant; ***P < 0.001. Reproduced with permission from ref (207). Copyright 2017 Nature Publishing group.