Skip to main content
. Author manuscript; available in PMC: 2021 Sep 17.
Published in final edited form as: Cancer Treat Res Commun. 2020 Sep 17;25:100210. doi: 10.1016/j.ctarc.2020.100210

Fig. 4. Effect of MGN and Mito-MGN on the proliferation of G361 melanoma cells.

Fig. 4.

(A,B) G361 melanoma cells were treated with MGN (A) or Mito-MGN (B). Cell proliferation was monitored in real time using the IncuCyte imager. (C) Representative phase contrast images (10×). (D) Cells were treated with MGN or Mito-MGN, and cell growth was monitored continuously using the IncuCyte instrument. The cell confluence (as control groups reach 98% confluence) is plotted against concentration. Dashed lines represent the fitting curves used for determination of the IC50 values. (E) Effect of MGN and Mito-MGN on the activity of mitochondrial complex I. G361 cells were pretreated with MGN and Mito-MGN for 24 h. The mitochondrial complex I OCR values are plotted against the concentrations of MGN and Mito-MGN. Dashed lines represent the fitting curves used to determine the IC50 values.