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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Gastroenterol Clin North Am. 2020 Mar 29;49(2):191–199. doi: 10.1016/j.gtc.2020.01.002

Fig. 1.

Fig. 1.

Effects of HAV exposure in immunocompetent and immunosuppressed patients. Patients immunized against HAV before exposure can clear the virus via preformed neutralizing antibodies. Nonimmune patients who are immunocompetent typically clear the virus after the infectious hepatitis, whereas immunosuppressed patients may sustain a chronic viremia. In rare cases, both immunocompetent and immunosuppressed hosts may manifest an unusual presentation of HAV, including but not limited to liver failure, relapsing hepatitis, and prolonged cholestasis.