Table 1.
Epidemiology | Estimated 1.4 million cases per year globally Infections can be sporadic or epidemic |
Transmission | Fecal-oral via Person-to-person contact Consumption of contaminated food or water |
Diagnosis | Presence of IgM antibodies to HAV |
Treatment | Supportive |
Classical presentation | Children Asymptomatic Adults Jaundice, hyperbilirubinemia, RUQ pain, anorexia |
Unusual presentations | Relapsing hepatitis Prolonged cholestasis Acute liver failure |
Prevention | HAV vaccine |
Postexposure prophylaxis | HAV vaccine HAV immune globulin |
Abbreviation: RUQ, right upper quadrant.