Table 3.
The results of immunohistochemistry staining for ovarian mucinous carcinoma
Ovarian mucinous carcinoma with infiltrative invasion |
Ovarian mucinous carcinoma with expansile invasion |
p-Value | ||||
---|---|---|---|---|---|---|
Molecule | n = 25 | n = 24 | ||||
CK7 (n (%)) | Positive | 24 | (96.0) | 24 | (100.0) | 0.99 |
Negative | 1 | (4.0) | 0 | (0.0) | ||
CK20 (n (%)) | Positive | 11 | (44.0) | 15 | (62.5) | 0.24 |
Negative | 14 | (56.0) | 9 | (37.5) | ||
CDX2 (n (%)) | Positive | 21 | (84.0) | 23 | (95.8) | 0.35 |
Negative | 4 | (16.0) | 1 | (4.2) | ||
HER-2 (n (%)) | Positive | 7 | (28.0) | 10 | (41.7) | 0.38 |
Negative | 18 | (72.0) | 14 | (58.3) | ||
CK 5/6 (n (%)) | Positive | 9 | (36.0) | 1 | (4.2) | 0.01 |
Negative | 16 | (64.0) | 23 | (95.8) | ||
Androgen receptor (n (%)) | Positive | 2 | (8.0) | 0 | (0.0) | 0.49 |
Negative | 23 | (92.0) | 24 | (100.0) | ||
ALDH1 (n (%)) | Positive | 9 | (36.0) | 10 | (41.7) | 0.77 |
Negative | 16 | (64.0) | 14 | (58.3) | ||
CD24 (n (%)) | Positive | 6 | (24.0) | 0 | (0.0) | 0.02 |
Negative | 19 | (76.0) | 24 | (100.0) | ||
CD133 (n (%)) | Positive | 8 | (32.0) | 5 | (20.8) | 0.52 |
Negative | 17 | (68.0) | 19 | (79.2) | ||
PD-1 (n (%)) | Positive | 2 | (8.0) | 0 | (0.0) | 0.49 |
Negative | 23 | (92.0) | 24 | (100.0) | ||
PD-L1 (n (%)) | Positive | 6 | (24.0) | 6 | (25.0) | 0.99 |
Negative | 19 | (76.0) | 18 | (75.0) | ||
ZEB1 (n (%)) | Positive | 1 | (4.0) | 1 | (4.2) | 0.99 |
Negative | 24 | (96.0) | 23 | (95.8) | ||
c-Met (n (%)) | Positive | 6 | (24.0) | 4 | (16.7) | 0.73 |
Negative | 19 | (76.0) | 20 | (83.3) | ||
EGFR (n (%)) | Positive | 7 | (28.0) | 0 | (0.0) | < 0.01 |
Negative | 18 | (72.0) | 24 | (100.0) | ||
Snail-2 (n (%)) | Positive | 1 | (4.0) | 1 | (4.2) | 0.99 |
Negative | 24 | (96.0) | 23 | (95.8) |
Abbreviations: CK7 Cytokeratin 7, CK20 Cytokeratin 20, CDX2 Caudal type homeobox 2, HER-2 Human epidermal growth factor receptor 2, CK5/6 Cytokeratin 5/6, ALDH1 Aldehyde dehydrogenase 1, CD24 Cluster of differentiation 24, CD133 Cluster of differentiation 133, PD-1 Programmed cell death 1, PD-L1 Programmed cell death 1- ligand 1, ZEB1 Zinc finger E-box binding homeobox 1, EGFR Epithelial growth factor receptor