Table 2.
Correlation and linear regression analyses of the associations of lipid profiles with UACR
| Variables | r | P value | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|---|---|
| Standarized β | P value | Standarized β | P value | Standarized β | P value | |||
| Female | ||||||||
| TG | 0.151 | < 0.001 | 0.086 | < 0.001 | 0.066 | < 0.001 | 0.029 | < 0.001 |
| TG/HDL-C | 0.162 | < 0.001 | 0.086 | < 0.001 | 0.068 | < 0.001 | 0.030 | < 0.001 |
| Non-HDL-C/HDL-C | 0.068 | < 0.001 | 0.062 | < 0.001 | 0.045 | < 0.001 | 0.015 | 0.014 |
| Male | ||||||||
| TG | 0.094 | < 0.001 | 0.091 | < 0.001 | 0.047 | < 0.001 | 0.019 | 0.054 |
| TG/HDL-C | 0.106 | < 0.001 | 0.089 | < 0.001 | 0.049 | < 0.001 | 0.022 | 0.025 |
| Non-HDL-C/HDL-C | 0.033 | 0.001 | 0.058 | < 0.001 | 0.026 | 0.007 | 0.007 | 0.440 |
Model 1: adjusted for center, age.
Model 2: additionally adjusted for ALT, γ-GGT, BMI, smoking, drinking, cardiovascular disease, eGFR.
Model 3: additionally adjusted for HbA1c, SBP, DBP, pulse, HOMA-IR and use of anti-diabetic medication.
UACR, TG, TG/HDL-C levels were logarithmically transformed to achieve a normal distribution.
Abbreviations: r correlation coefficient; β regression coefficient; UACR urinary albumin-creatinine ratio; TG triglyceride; HDL-C high-density lipoprotein cholesterol; non-HDL-C non-high-density lipoprotein cholesterol; eGFR estimated glomerular filtration rate; ALT alanine transaminase; γ-GGT γ-glutamyl transpeptidase; BMI body mass index; SBP systolic blood pressure; DBP diastolic blood pressure; HbA1c hemoglobin A1c; HOMA-IR homeostasis model assessment of insulin resistance