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. 2021 Feb 15;20:13. doi: 10.1186/s12944-021-01442-8

Table 2.

Correlation and linear regression analyses of the associations of lipid profiles with UACR

Variables r P value Model 1 Model 2 Model 3
Standarized β P value Standarized β P value Standarized β P value
Female
 TG 0.151 < 0.001 0.086 < 0.001 0.066 < 0.001 0.029 < 0.001
 TG/HDL-C 0.162 < 0.001 0.086 < 0.001 0.068 < 0.001 0.030 < 0.001
 Non-HDL-C/HDL-C 0.068 < 0.001 0.062 < 0.001 0.045 < 0.001 0.015 0.014
Male
 TG 0.094 < 0.001 0.091 < 0.001 0.047 < 0.001 0.019 0.054
 TG/HDL-C 0.106 < 0.001 0.089 < 0.001 0.049 < 0.001 0.022 0.025
 Non-HDL-C/HDL-C 0.033 0.001 0.058 < 0.001 0.026 0.007 0.007 0.440

Model 1: adjusted for center, age.

Model 2: additionally adjusted for ALT, γ-GGT, BMI, smoking, drinking, cardiovascular disease, eGFR.

Model 3: additionally adjusted for HbA1c, SBP, DBP, pulse, HOMA-IR and use of anti-diabetic medication.

UACR, TG, TG/HDL-C levels were logarithmically transformed to achieve a normal distribution.

Abbreviations: r correlation coefficient; β regression coefficient; UACR urinary albumin-creatinine ratio; TG triglyceride; HDL-C high-density lipoprotein cholesterol; non-HDL-C non-high-density lipoprotein cholesterol; eGFR estimated glomerular filtration rate; ALT alanine transaminase; γ-GGT γ-glutamyl transpeptidase; BMI body mass index; SBP systolic blood pressure; DBP diastolic blood pressure; HbA1c hemoglobin A1c; HOMA-IR homeostasis model assessment of insulin resistance