Table 1. Brain Uptake of Radioactivity after the Injection of Each ¹⁸F-Labeled BIP Derivative in Normal Mice^a and the Ratio of Their Radioactivity Accumulation (2 min/60 min).

	% ID/g in the brain				ratio
compd	2 min	10 min	30 min	60 min	2 min/60 min
[18F]Br-BIPF	6.29 (0.91)	2.64 (0.15)	1.81 (0.16)	1.92 (0.22)	3.28
[18F]Cl-BIPF	6.38 (0.55)	2.86 (0.22)	2.31 (0.19)	2.16 (0.22)	2.95
[18F]Me-BIPF	6.79 (0.83)	3.83 (0.51)	1.96 (0.17)	1.89 (0.11)	3.59
[18F]OMe-BIPF	5.15 (0.20)	3.01 (0.33)	1.88 (0.33)	1.83 (0.17)	2.81
[18F]H-BIPF	4.84 (0.44)	2.87 (0.07)	1.99 (0.20)	2.02 (0.21)	2.39
[18F]IBIPF1b	6.22 (0.70)	3.68 (0.32)	2.77 (0.52)	2.01 (0.28)	3.09
[18F]RO-948	4.16 (0.35)	1.36 (0.17)	0.24 (0.08)	0.13 (0.07)	32.0

^aEach value represents the mean (SD) of five animals.

^bThe data were reported previously.¹⁵