. 2021 Feb 1;12(2):267–274. doi: 10.1021/acsmedchemlett.0c00647

Table 2. In Vitro Activity of 17–20 on FXR in a Hybrid Reporter Gene Assay^a.

Maximum relative activation (max. rel. act.) and remaining activity (remain. act.) correspond to the activity of 1 μM GW4064 (1). Data are reported as mean ± SEM, n ≥ 3. K_d values were obtained from ITC with recombinant FXR LBD.

Table 2. In Vitro Activity of 17–20 on FXR in a Hybrid Reporter Gene Assaya.

Table 2. In Vitro Activity of 17–20 on FXR in a Hybrid Reporter Gene Assay^a.