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Receptor binding assays of intact and cleaved GLP-1 to GLP-1R
| Intact GLP-1(7–36) | Cleaved GLP-1(9–36) | Ref. | |
|---|---|---|---|
| Saturation binding assay KD | 1.29 ± 0.26 AU | 0.214 ± 0.08 AU | Kuc et al. (2014) |
| Saturation binding assay BMAX | 57.0 ± 14.5 AU | 2.69 ± 0.74 AU | Kuc et al. (2014) |
| SPA binding assay Ki | 0.102 nM | 156 nM | Kuc et al. (2014) |
| cAMP assay EC50 | 0.072 nM | 7270 nM | Kuc et al. (2014) |
| cAMP assay EMAX | 104% | 8.93% | Kuc et al. (2014) |
