Table 3.
Gene ontology (GO) lerms enriched for SNP-annotated genes with FDR ≤ 0.05
| Traits | GO terms | Term description | Gene counts | FDR |
|---|---|---|---|---|
| T2D | GO.0031016 | Pancreas development | 9 | 9.73E–06 |
| GO.0010565 | Regulation of cellular ketone metabolic process | 11 | 3.40E–05 | |
| GO.0031018 | Endocrine pancreas development | 7 | 3.40E–05 | |
| GO.0048522 | Positive regulation of cellular process | 49 | 3.40E–05 | |
| GO.0048518 | Positive regulation of biological process | 53 | 3.62E–05 | |
| CAD | GO.0034185 | Apolipoprotein binding | 3 | 1.40E–02 |
| GO.0005515 | Protein binding | 24 | 1.50E–02 | |
| Pleiotropic | GO:0043102 | Amino acid salvage | 2 | 3.51E–02 |
| GO:0071265 | l-Methionine biosynthetic process | 2 | 3.57E–02 | |
| GO:0046883 | Regulation of hormone secrction | 4 | 4.14E–02 | |
| GO:0071267 | l-Methionine salvage | 2 | 4.38E–02 |