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. Author manuscript; available in PMC: 2021 Feb 15.
Published in final edited form as: Mol Genet Genomics. 2020 Mar 11;295(3):607–619. doi: 10.1007/s00438-020-01651-3

Table4.

Genetic association between T2D and CAD by Mendelian randomization analysis on 16 T2D-associated genes

Method nSNP β (95% CI) p
MR Egger 17 0.124 (0.066, 0.154) 0.050
Weighted median 17 0.096 (0.067, 0.111) 0.001
Inverse variance weighted 17 0.076 (0.05, 0.09) 0.003
Simple mode 17 0.074 (0.019, 0.103) 0.200
Weighted mode 17 0.099 (0.071,0.114) 0.003

Detailed SNPs information is exhibited in Table S5

nSNP number of SNPs applied in the test, β effect size, 95% CI 95% confidence interval, p p value