Covid Positive | Covid negative | Percent with feature | Percent COVID positive | Hazards ratio | 95% CI | P | Comments | ||
ALL PATIENTS | |||||||||
Sarcoidosis | 66 | 1906 | 1972 | 3.35% | 9.15 | 2.249-37.253 | 0.002 | ||
Cancer | 2 | 545 | 547 | 0.37% | |||||
LOCAL | |||||||||
OH/KY/IN | 3 | 538 | 541 | 0.55% | 1.5166 | 0.2544-9.041 | Cincinnati Clinic patients | ||
Cancer | 2 | 545 | 547 | 0.37% | Sarc versus cancer | ||||
Sarc patients | |||||||||
Male | 19 | 495 | 514 | 26.18% | 3.70% | 1.14 | 0.675-1.923 | >0.10 | |
Female | 47 | 1402 | 1449 | 73.82% | 3.24% | 9 no sex indicated | |||
Black | 11 | 371 | 382 | 20.07% | 2.88% | 0.796 | 0.4209-1.5066 | >0.10 | |
White | 55 | 1466 | 1521 | 79.93% | 3.62% | 9 patients biracial | |||
Roommate with COVID | |||||||||
yes | 21 | 17 | 38 | 1.94% | 55.26% | 23.6772 | 15.769-35.5514 | <0.0001 | |
no | 45 | 1883 | 1928 | 98.22% | 2.33% | ||||
Health care provider | |||||||||
Yes | 12 | 197 | 209 | 10.65% | 5.74% | 1.8565 | 1.0099-3.4127 | 0.0464 | |
no | 54 | 1692 | 1746 | 88.95% | 3.09% | ||||
Current meds | |||||||||
Prednisone | 24 | 755 | 779 | 39.50% | 3.08% | 0.8751 | 0.5343-1.4332 | >0.10 | |
No prednisone | 42 | 1151 | 1193 | 60.50% | 3.52% | ||||
Prednisone >10 mg or more | 13 | 361 | 374 | 18.97% | 3.48% | 1.048 | 0.5774-1.9022 | >0.10 | |
Prednisone < 10 mg | 53 | 1545 | 1598 | 81.03% | 3.32% | ||||
Plaquenil | 7 | 239 | 246 | 12.47% | 2.85% | 0.8324 | 0.3846-1.8016 | >0.10 | |
No plaquenil | 59 | 1667 | 1726 | 87.53% | 3.42% | ||||
anti-TNF | 6 | 183 | 189 | 9.58% | 3.17% | 0.9434 | 0.4131-2.1542 | >0.10 | |
no anti-TNF | 60 | 1723 | 1783 | 90.42% | 3.37% | ||||
Cytotoxic | 21 | 537 | 558 | 28.30% | 3.76% | 1.1826 | 0.7111-1.9666 | >0.10 | |
No cytotoxic | 45 | 1369 | 1414 | 71.70% | 3.18% | ||||
Rituximab | 6 | 42 | 48 | 2.43% | 12.50% | 4.0083 | 1.8213-8.8217 | 0.0006 | |
No rituximab | 60 | 1864 | 1924 | 97.57% | 3.12% | ||||
Underlying | |||||||||
COPD | 12 | 321 | 333 | 16.89% | 3.60% | 1.0938 | 0.5917-2.0217 | >0.10 | |
54 | 1585 | 1639 | 83.11% | 3.29% | |||||
Diabetes | 5 | 292 | 297 | 15.06% | 1.68% | 0.4623 | 0.1873-1.1408 | 0.0941 | |
61 | 1614 | 1675 | 84.94% | 3.64% | |||||
Heart disease | 8 | 254 | 262 | 13.29% | 3.05% | 0.9002 | 0.4348-1.8637 | >0.10 | |
58 | 1652 | 1710 | 86.71% | 3.39% | |||||
Hypertension | 15 | 480 | 495 | 25.10% | 3.03% | 0.8776 | 0.498-1.5466 | >0.10 | |
51 | 1426 | 1477 | 74.90% | 3.45% | |||||
Organ involved | |||||||||
Lung | 58 | 1596 | 1654 | 83.87% | 3.51% | 1.3939 | 0.6721-2.8907 | >0.10 | |
8 | 310 | 318 | 16.13% | 2.52% | |||||
Cardiac sarc | 12 | 278 | 290 | 14.71% | 4.14% | 1.3303 | 0.7206-2.4557 | >0.10 | |
54 | 1628 | 1682 | 85.29% | 3.21% | |||||
Neuro sarc | 11 | 184 | 195 | 9.89% | 5.64% | 1.8228 | 0.9704-3.4229 | 0.0619 | |
55 | 1722 | 1777 | 90.11% | 3.10% | |||||
Origin | |||||||||
US | 50 | 1551 | 1601 | 81.19% | 3.12% | 0.7516 | 0.4269-1.3232 | >0.10 | |
non US | 15 | 346 | 361 | 18.31% | 4.16% | No country entered: 10 | |||
OH/KY/IN | 3 | 538 | 541 | 27.43% | 0.55% | ||||
63 | 1368 | 1431 | 72.57% | 4.40% | |||||
Sarcoid age | |||||||||
Covid Positive | 54.5 ± 11.39 years | 0.088 | |||||||
Covid negative | 53.0 ± 9.60 years | ||||||||
COVID outcome | Home | Hospital | ICU | Ventilator | |||||
Sarc | 44 | 9 | 3 | 0 | |||||
Cancer | 1 | 1 | 0 | 0 | |||||
Sarc ≥ 5 yr | 48 | 1274 | 1322 | 67.35% | 3.63% | 1.3321 | 0.7629-2.359 | >0.01 | |
Sarc < 5 yr | 16 | 571 | 587 | 29.90% | 2.73% | ||||
Hospital considered bad outcome | |||||||||
COVID positive | Home | Hospital | Hazard ration for | ||||||
Prednisone | Hospitalization | ||||||||
Yes | 20 | 4 | 24 | 1.22% | 83.33% | 0.875 | 0.2941-2.6036 | >0.10 | |
No | 34 | 8 | 42 | 2.14% | 80.95% | ||||
If prednisone | |||||||||
Prednisone ≥ 10 mg | 11 | 2 | 13 | 19.70% | 15.38% | 0.8154 | 0.2027-3.2794 | >0.10 | |
Prednisone < 10mg | 43 | 10 | 53 | 80.30% | 18.87% | ||||
Infliximab | |||||||||
Yes | 4 | 2 | 6 | 0.31% | 66.67% | 0.8154 | 0.2027-3.2794 | >0.10 | |
No | 50 | 10 | 60 | 3.06% | 83.33% | ||||
Plaquenil | |||||||||
Yes | 6 | 1 | 7 | 0.36% | 85.71% | 0.7662 | 0.1156-5.9785 | >0.10 | |
No | 48 | 11 | 59 | 3.01% | 81.36% | ||||
Cytotoxic | |||||||||
Yes | 14 | 7 | 21 | 1.07% | 66.67% | 3 | 1.0773-83539 | 0.0355 | |
No | 40 | 5 | 45 | 2.29% | 88.89% | ||||
Rituximab | |||||||||
Yes | 6 | 0 | 6 | 0.31% | 100.00% | 0.3486 | 0.02303-5.2723 | >0.10 | |
No | 48 | 12 | 60 | 3.06% | 80.00% |
* 9 patients did not indicate sex.
† 9 patients biracial
¶ Included inflixiamb, adlimumab, and biosimilars
§ Included methotrexate, azathioprine, mycophenolate, and leflunomide
** 63 patients did not provide information regarding duration of disease.
UC: University of Cincinnati clinic