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. 2020 Dec 16;37(4):e2020009. doi: 10.36141/svdld.v37i4.10726
Covid Positive Covid negative Percent with feature Percent COVID positive Hazards ratio 95% CI P Comments
ALL PATIENTS
Sarcoidosis 66 1906 1972 3.35% 9.15 2.249-37.253 0.002
Cancer 2 545 547 0.37%
LOCAL
OH/KY/IN 3 538 541 0.55% 1.5166 0.2544-9.041 Cincinnati Clinic patients
Cancer 2 545 547 0.37% Sarc versus cancer
Sarc patients
Male 19 495 514 26.18% 3.70% 1.14 0.675-1.923 >0.10
Female 47 1402 1449 73.82% 3.24% 9 no sex indicated
Black 11 371 382 20.07% 2.88% 0.796 0.4209-1.5066 >0.10
White 55 1466 1521 79.93% 3.62% 9 patients biracial
Roommate with COVID
yes 21 17 38 1.94% 55.26% 23.6772 15.769-35.5514 <0.0001
no 45 1883 1928 98.22% 2.33%
Health care provider
Yes 12 197 209 10.65% 5.74% 1.8565 1.0099-3.4127 0.0464
no 54 1692 1746 88.95% 3.09%
Current meds
Prednisone 24 755 779 39.50% 3.08% 0.8751 0.5343-1.4332 >0.10
No prednisone 42 1151 1193 60.50% 3.52%
Prednisone >10 mg or more 13 361 374 18.97% 3.48% 1.048 0.5774-1.9022 >0.10
Prednisone < 10 mg 53 1545 1598 81.03% 3.32%
Plaquenil 7 239 246 12.47% 2.85% 0.8324 0.3846-1.8016 >0.10
No plaquenil 59 1667 1726 87.53% 3.42%
anti-TNF 6 183 189 9.58% 3.17% 0.9434 0.4131-2.1542 >0.10
no anti-TNF 60 1723 1783 90.42% 3.37%
Cytotoxic 21 537 558 28.30% 3.76% 1.1826 0.7111-1.9666 >0.10
No cytotoxic 45 1369 1414 71.70% 3.18%
Rituximab 6 42 48 2.43% 12.50% 4.0083 1.8213-8.8217 0.0006
No rituximab 60 1864 1924 97.57% 3.12%
Underlying
COPD 12 321 333 16.89% 3.60% 1.0938 0.5917-2.0217 >0.10
54 1585 1639 83.11% 3.29%
Diabetes 5 292 297 15.06% 1.68% 0.4623 0.1873-1.1408 0.0941
61 1614 1675 84.94% 3.64%
Heart disease 8 254 262 13.29% 3.05% 0.9002 0.4348-1.8637 >0.10
58 1652 1710 86.71% 3.39%
Hypertension 15 480 495 25.10% 3.03% 0.8776 0.498-1.5466 >0.10
51 1426 1477 74.90% 3.45%
Organ involved
Lung 58 1596 1654 83.87% 3.51% 1.3939 0.6721-2.8907 >0.10
8 310 318 16.13% 2.52%
Cardiac sarc 12 278 290 14.71% 4.14% 1.3303 0.7206-2.4557 >0.10
54 1628 1682 85.29% 3.21%
Neuro sarc 11 184 195 9.89% 5.64% 1.8228 0.9704-3.4229 0.0619
55 1722 1777 90.11% 3.10%
Origin
US 50 1551 1601 81.19% 3.12% 0.7516 0.4269-1.3232 >0.10
non US 15 346 361 18.31% 4.16% No country entered: 10
OH/KY/IN 3 538 541 27.43% 0.55%
63 1368 1431 72.57% 4.40%
Sarcoid age
Covid Positive 54.5 ± 11.39 years 0.088
Covid negative 53.0 ± 9.60 years
COVID outcome Home Hospital ICU Ventilator
Sarc 44 9 3 0
Cancer 1 1 0 0
Sarc ≥ 5 yr 48 1274 1322 67.35% 3.63% 1.3321 0.7629-2.359 >0.01
Sarc < 5 yr 16 571 587 29.90% 2.73%
Hospital considered bad outcome
COVID positive Home Hospital Hazard ration for
Prednisone Hospitalization
Yes 20 4 24 1.22% 83.33% 0.875 0.2941-2.6036 >0.10
No 34 8 42 2.14% 80.95%
If prednisone
Prednisone ≥ 10 mg 11 2 13 19.70% 15.38% 0.8154 0.2027-3.2794 >0.10
Prednisone < 10mg 43 10 53 80.30% 18.87%
Infliximab
Yes 4 2 6 0.31% 66.67% 0.8154 0.2027-3.2794 >0.10
No 50 10 60 3.06% 83.33%
Plaquenil
Yes 6 1 7 0.36% 85.71% 0.7662 0.1156-5.9785 >0.10
No 48 11 59 3.01% 81.36%
Cytotoxic
Yes 14 7 21 1.07% 66.67% 3 1.0773-83539 0.0355
No 40 5 45 2.29% 88.89%
Rituximab
Yes 6 0 6 0.31% 100.00% 0.3486 0.02303-5.2723 >0.10
No 48 12 60 3.06% 80.00%

* 9 patients did not indicate sex.

† 9 patients biracial

¶ Included inflixiamb, adlimumab, and biosimilars

§ Included methotrexate, azathioprine, mycophenolate, and leflunomide

** 63 patients did not provide information regarding duration of disease.

UC: University of Cincinnati clinic