Site: Netherlands |
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Covid Positive |
Covid negative |
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Percent with feature |
Percent COVID positive |
Hazard s ratio |
95% CI |
P |
Comments |
Sarcoidosis (996 who live in the Netherlands , out of 1034 respondents ) |
23 |
973 |
996 |
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2.31% |
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Male |
6 |
418 |
424 |
21.60% |
1.42% |
0.4745 |
0.1187-1.1932 |
>0.10 |
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Female |
17 |
553 |
570 |
29.04% |
2.98% |
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2 no sex indicated |
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White |
22 |
932 |
954 |
48.60% |
2.31% |
0.9682 |
0.1337-7.0165 |
>0.10 |
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Other |
1 |
41 |
42 |
2.14% |
2.38% |
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BMI categories |
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BMI < 25 |
8 |
348 |
356 |
18.14% |
2.25% |
0.958 |
0.4029-2.2323 |
>0.10 |
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BMI ≥ 25 |
15 |
623 |
638 |
32.50% |
2.35% |
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Current meds |
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Prednisone |
4 |
194 |
198 |
10.09% |
2.02% |
0.84585 |
0.2919-2.4661 |
>0.01 |
of 28 patients the dose is missing |
No prednisone |
19 |
779 |
987 |
40.65% |
2.38% |
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Prednisone ≥ 10 mg |
2 |
76 |
78 |
3.97% |
2.56% |
1.1795 |
0.1701-8.1803 |
>0.10 |
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Prednisone < 10mg |
2 |
90 |
92 |
4.69% |
2.17% |
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Plaquenil |
1 |
57 |
58 |
2.95% |
1.72% |
0.7351 |
0.1008-5.3585 |
>0.10 |
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No plaquenil |
22 |
916 |
938 |
47.78% |
2.35% |
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anti-TNF (infliximab (6), adalimumab (7)) |
0 |
76 |
76 |
3.87% |
0.00% |
0.2545 |
0.01561-4.14497 |
>0.10 |
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no anti-TNF (de lege cellen uit dezelfde kolommen) |
23 |
897 |
920 |
46.87% |
2.50% |
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1 patient was treated with both infliximab and adalimumab |
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Cytotoxic (methotrexa te (2), azathioprine (3), leflunomide (5)) |
2 |
227 |
229 |
11.67% |
0.87% |
0.319 |
0.07536-1.3502 |
>0.10 |
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No cytotoxic (lege cellen in dezelfde kolommen) |
21 |
746 |
767 |
39.07% |
2.74% |
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3 patients were treated with both methotrexat e and azathioprine |
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Rituximab |
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yes |
0 |
1 |
1 |
0.05% |
0.00% |
10.5957 |
0.9295-120.7801 |
0.0573 |
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no |
23 |
972 |
995 |
50.69% |
2.31% |
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Current medication |
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yes |
7 |
515 |
572 |
26.74% |
1.34% |
0.40 |
0.165-0.958 |
<0.05 |
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no |
16 |
458 |
474 |
24.04% |
3.38% |
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Underlying |
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COPD |
0 |
20 |
20 |
1.02% |
0.00% |
0.9899 |
0.6217-15.7596 |
>0.10 |
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23 |
953 |
976 |
49.72% |
2.36% |
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Asthma |
2 |
80 |
82 |
4.18% |
2.44% |
1.0616 |
0.2534-4.448 |
>0.10 |
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21 |
893 |
914 |
46.56% |
2.30% |
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Diabetes |
2 |
47 |
49 |
2.50% |
4.08% |
1.8406 |
0.441-7.628 |
>0.10 |
(past) use of prednison can be studied additionally |
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21 |
926 |
947 |
48.24% |
2.22% |
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Heart failure |
0 |
27 |
27 |
1.38% |
0.00% |
0.7371 |
0.04592-11.8322 |
>0.10 |
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23 |
946 |
969 |
49.36% |
2.37% |
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Circulation |
2 |
35 |
37 |
1.88% |
5.41% |
2.4685 |
0.601-10.1387 |
>0.10 |
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21 |
938 |
959 |
48.85% |
2.19% |
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Hypertension |
1 |
107 |
108 |
5.50% |
0.93% |
0.3737 |
0.05088-2.7452 |
>0.10 |
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22 |
866 |
888 |
45.24% |
2.48% |
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Cancer |
0 |
20 |
20 |
1.02% |
0.00% |
0.9899 |
0.06217-15.7596 |
>0.10 |
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23 |
953 |
976 |
49.72% |
2.36% |
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Organ involved |
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Lung |
20 |
820 |
840 |
42.79% |
2.38% |
1.2381 |
0.3724-4.1165 |
>0.10 |
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no Lung |
3 |
153 |
156 |
7.95% |
1.92% |
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heart |
0 |
115 |
115 |
5.86% |
0.00% |
0.1618 |
0.009892-2.645 |
>0.10 |
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no heart |
23 |
858 |
881 |
44.88% |
2.61% |
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CNS |
1 |
118 |
119 |
6.06% |
0.84% |
0.335 |
0.04557-2.426 |
>0.10 |
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no CNS |
22 |
855 |
877 |
44.68% |
2.51% |
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Sarcoid age |
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COVID positive |
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55.3 ± 6.0 years |
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COVID negative |
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55.0±10. 8 years |
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COVID uncertain |
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50.5 ± 11.0 years |
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COVID outcome |
Home |
Hospital |
ICU |
Vent |
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Sarc |
20 |
3 |
0 |
0.00% |
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Sarc ≥ 5 yr |
15 |
678 |
693 |
70.14% |
2.16% |
0.912 |
0.3758-2.2141 |
>0.10 |
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Sarc < 5 yr |
7 |
288 |
295 |
29.86% |
2.37% |
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8 unknown |
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988 |
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Roommates with COVID-19 |
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yes |
11 |
30 |
41 |
4.12% |
26.83% |
21.3516 |
10.0247-45-4768 |
<0.0001 |
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no |
12 |
943 |
955 |
95.88% |
1.26% |
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996 |
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Work in healthcare |
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Yes |
4 |
99 |
103 |
10.34% |
3.88% |
1.8252 |
0.6331-5.2618 |
>0.10 |
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No |
19 |
874 |
893 |
89.66% |
2.13% |
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996 |
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COVID positive |
Home |
Hospital |
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Perce nt on drug |
Percent treate d in hospit al |
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If in hospital, considered |
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bad outcome |
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Hazard ration for |
Prednisone |
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Hospitalization |
Yes |
4 |
0 |
4 |
17.39% |
0.00% |
0.5714 |
0.03487-9.3644 |
>0.10 |
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No |
16 |
3 |
19 |
82.61% |
15.79% |
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Prednisone ≥ 10 mg |
2 |
0 |
2 |
50.00% |
0.00% |
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TOO SMALL |
Prednisone < 10mg |
2 |
0 |
2 |
50.00% |
0.00% |
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Infliximab |
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there were no COVID - 19 positive patients who were treated with infliximab |
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Plaquenil |
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Yes |
1 |
0 |
1 |
4.35% |
0.00% |
1.6428 |
0.1236-21.835 |
>0.10 |
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No |
19 |
3 |
22 |
95.65% |
13.64% |
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Cytotoxic |
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yes |
2 |
0 |
2 |
8.70% |
0.00% |
1.0476 |
0.06994-15.6914 |
>0.10 |
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no |
18 |
3 |
21 |
91.30% |
14.29% |
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Rituximab |
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none of the COVID-19 positive patients was treated with rituximab |
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