| Site: Netherlands | |||||||||
| Covid Positive | Covid negative | Percent with feature | Percent COVID positive | Hazard s ratio | 95% CI | P | Comments | ||
| Sarcoidosis (996 who live in the Netherlands , out of 1034 respondents ) | 23 | 973 | 996 | 2.31% | |||||
| Male | 6 | 418 | 424 | 21.60% | 1.42% | 0.4745 | 0.1187-1.1932 | >0.10 | |
| Female | 17 | 553 | 570 | 29.04% | 2.98% | 2 no sex indicated | |||
| White | 22 | 932 | 954 | 48.60% | 2.31% | 0.9682 | 0.1337-7.0165 | >0.10 | |
| Other | 1 | 41 | 42 | 2.14% | 2.38% | ||||
| BMI categories | |||||||||
| BMI < 25 | 8 | 348 | 356 | 18.14% | 2.25% | 0.958 | 0.4029-2.2323 | >0.10 | |
| BMI ≥ 25 | 15 | 623 | 638 | 32.50% | 2.35% | ||||
| Current meds | |||||||||
| Prednisone | 4 | 194 | 198 | 10.09% | 2.02% | 0.84585 | 0.2919-2.4661 | >0.01 | of 28 patients the dose is missing |
| No prednisone | 19 | 779 | 987 | 40.65% | 2.38% | ||||
| Prednisone ≥ 10 mg | 2 | 76 | 78 | 3.97% | 2.56% | 1.1795 | 0.1701-8.1803 | >0.10 | |
| Prednisone < 10mg | 2 | 90 | 92 | 4.69% | 2.17% | ||||
| Plaquenil | 1 | 57 | 58 | 2.95% | 1.72% | 0.7351 | 0.1008-5.3585 | >0.10 | |
| No plaquenil | 22 | 916 | 938 | 47.78% | 2.35% | ||||
| anti-TNF (infliximab (6), adalimumab (7)) | 0 | 76 | 76 | 3.87% | 0.00% | 0.2545 | 0.01561-4.14497 | >0.10 | |
| no anti-TNF (de lege cellen uit dezelfde kolommen) | 23 | 897 | 920 | 46.87% | 2.50% | 1 patient was treated with both infliximab and adalimumab | |||
| Cytotoxic (methotrexa te (2), azathioprine (3), leflunomide (5)) | 2 | 227 | 229 | 11.67% | 0.87% | 0.319 | 0.07536-1.3502 | >0.10 | |
| No cytotoxic (lege cellen in dezelfde kolommen) | 21 | 746 | 767 | 39.07% | 2.74% | 3 patients were treated with both methotrexat e and azathioprine | |||
| Rituximab | |||||||||
| yes | 0 | 1 | 1 | 0.05% | 0.00% | 10.5957 | 0.9295-120.7801 | 0.0573 | |
| no | 23 | 972 | 995 | 50.69% | 2.31% | ||||
| Current medication | |||||||||
| yes | 7 | 515 | 572 | 26.74% | 1.34% | 0.40 | 0.165-0.958 | <0.05 | |
| no | 16 | 458 | 474 | 24.04% | 3.38% | ||||
| Underlying | |||||||||
| COPD | 0 | 20 | 20 | 1.02% | 0.00% | 0.9899 | 0.6217-15.7596 | >0.10 | |
| 23 | 953 | 976 | 49.72% | 2.36% | |||||
| Asthma | 2 | 80 | 82 | 4.18% | 2.44% | 1.0616 | 0.2534-4.448 | >0.10 | |
| 21 | 893 | 914 | 46.56% | 2.30% | |||||
| Diabetes | 2 | 47 | 49 | 2.50% | 4.08% | 1.8406 | 0.441-7.628 | >0.10 | (past) use of prednison can be studied additionally |
| 21 | 926 | 947 | 48.24% | 2.22% | |||||
| Heart failure | 0 | 27 | 27 | 1.38% | 0.00% | 0.7371 | 0.04592-11.8322 | >0.10 | |
| 23 | 946 | 969 | 49.36% | 2.37% | |||||
| Circulation | 2 | 35 | 37 | 1.88% | 5.41% | 2.4685 | 0.601-10.1387 | >0.10 | |
| 21 | 938 | 959 | 48.85% | 2.19% | |||||
| Hypertension | 1 | 107 | 108 | 5.50% | 0.93% | 0.3737 | 0.05088-2.7452 | >0.10 | |
| 22 | 866 | 888 | 45.24% | 2.48% | |||||
| Cancer | 0 | 20 | 20 | 1.02% | 0.00% | 0.9899 | 0.06217-15.7596 | >0.10 | |
| 23 | 953 | 976 | 49.72% | 2.36% | |||||
| Organ involved | |||||||||
| Lung | 20 | 820 | 840 | 42.79% | 2.38% | 1.2381 | 0.3724-4.1165 | >0.10 | |
| no Lung | 3 | 153 | 156 | 7.95% | 1.92% | ||||
| heart | 0 | 115 | 115 | 5.86% | 0.00% | 0.1618 | 0.009892-2.645 | >0.10 | |
| no heart | 23 | 858 | 881 | 44.88% | 2.61% | ||||
| CNS | 1 | 118 | 119 | 6.06% | 0.84% | 0.335 | 0.04557-2.426 | >0.10 | |
| no CNS | 22 | 855 | 877 | 44.68% | 2.51% | ||||
| Sarcoid age | |||||||||
| COVID positive | 55.3 ± 6.0 years | ||||||||
| COVID negative | 55.0±10. 8 years | ||||||||
| COVID uncertain | 50.5 ± 11.0 years | ||||||||
| COVID outcome | Home | Hospital | ICU | Vent | |||||
| Sarc | 20 | 3 | 0 | 0.00% | |||||
| Sarc ≥ 5 yr | 15 | 678 | 693 | 70.14% | 2.16% | 0.912 | 0.3758-2.2141 | >0.10 | |
| Sarc < 5 yr | 7 | 288 | 295 | 29.86% | 2.37% | 8 unknown | |||
| 988 | |||||||||
| Roommates with COVID-19 | |||||||||
| yes | 11 | 30 | 41 | 4.12% | 26.83% | 21.3516 | 10.0247-45-4768 | <0.0001 | |
| no | 12 | 943 | 955 | 95.88% | 1.26% | ||||
| 996 | |||||||||
| Work in healthcare | |||||||||
| Yes | 4 | 99 | 103 | 10.34% | 3.88% | 1.8252 | 0.6331-5.2618 | >0.10 | |
| No | 19 | 874 | 893 | 89.66% | 2.13% | ||||
| 996 | |||||||||
| COVID positive | Home | Hospital | Perce nt on drug | Percent treate d in hospit al | If in hospital, considered | ||||
| bad outcome | |||||||||
| Hazard ration for | |||||||||
| Prednisone | Hospitalization | ||||||||
| Yes | 4 | 0 | 4 | 17.39% | 0.00% | 0.5714 | 0.03487-9.3644 | >0.10 | |
| No | 16 | 3 | 19 | 82.61% | 15.79% | ||||
| Prednisone ≥ 10 mg | 2 | 0 | 2 | 50.00% | 0.00% | TOO SMALL | |||
| Prednisone < 10mg | 2 | 0 | 2 | 50.00% | 0.00% | ||||
| Infliximab | there were no COVID - 19 positive patients who were treated with infliximab | ||||||||
| Plaquenil | |||||||||
| Yes | 1 | 0 | 1 | 4.35% | 0.00% | 1.6428 | 0.1236-21.835 | >0.10 | |
| No | 19 | 3 | 22 | 95.65% | 13.64% | ||||
| Cytotoxic | |||||||||
| yes | 2 | 0 | 2 | 8.70% | 0.00% | 1.0476 | 0.06994-15.6914 | >0.10 | |
| no | 18 | 3 | 21 | 91.30% | 14.29% | ||||
| Rituximab | |||||||||
| none of the COVID-19 positive patients was treated with rituximab | |||||||||