FIG. 3.
Phylogenetic analysis of HBV isolates for genotype and subgenotype determination. (A) Phylogenetic analysis of complete preS/S sequences of 43 HBV isolates, along with reference sequences of HBV strains belonging to different genotypes (A to J) derived from GenBank. (B) Phylogenetic analysis of complete preS/S sequences of 16 HBV isolates of genotypes C and D, along with reference sequences of HBV strains belonging to different subgenotypes (C and D) derived from GenBank. Phylogenetic tree was constructed using the Kimura 2 parameter model and neighbor-joining method by MEGA software version 5, and bootstrap resampling was carried out 5,000 times. The Tezpur sequences are indicated by respective isolate numbers beginning with “Kiran.”