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Effects of C + R + I (1 + 2+3) on the pro-inflammatory cytokine secretion in serum in LPS-induced ALI. Concentration of; (A) COX-2; (B) iNOS; (C) IL-1β, and,; (D) TNF-α. Values are expressed as the mean 7 SD (n1⁄43 or 4 in each group). *p < 0.05, **p < 0.01 as compared to the LPS group without C + R + I, #p < 0.05, ##p < 0.01 as compared to the normal control group without C + R + I. Effects of C + R + I on inhibition of MAPK-NF-κB in LPS-induced ALI.
