Table 2. Univariate and multivariate Cox regression survival analyses.

Parameters	Univariate analyses		Multivariate analyses
	Hazard ratio (95% CI)	P-value	Hazard ratio (95% CI)	P-value
CDC45 expression	0.558 (0.338–0.920)	0.022	0.509 (0.271–0.957)	0.035
Size	1.965 (1.201–3.213)	0.007	1.157 (0.614–2.177)	0.652
Metastasis	5.075 (2.673–9.636)	0.000	6.533 (2.916–14.635)	0.000
Microvascular invasion	1.879 (1.097–3.219)	0.022	1.015 (0.374–2.753)	0.977
Vessel invasion	2.035 (1.174–3.525)	0.011	1.636 (0.602–4.440)	0.334
Edmondson grade	2.696 (1.655–4.392)	0.000	2.082 (1.166–3.715)	0.013

Note.

Bold signifies p value<0.05.