TABLE 1.
List of mutations and amino acid changes observed in the sequenced genomes
| Isolate name | Nucleotide change(s)/SNPa,b | Gene(s) | Variance/amino acid change(s)a |
|---|---|---|---|
| NITMA1086 | C241T | Intergenic | upstream_gene_variant |
| NITMA1086 | C2695T | ORF1ab | synonymous_variant |
| NITMA1086 | C3037T | ORF1ab | synonymous_variant |
| NITMA1086 | G8371T | ORF1a | Q2702H |
| NITMA1086 | C14408T | ORF1b | P314L |
| NITMA1086 | C18877T | ORF1ab | synonymous_variant |
| NITMA1086 | G21468T | ORF1b | M2667I |
| NITMA1086 | A23403G | S | D614G |
| NITMA1086 | A24774T | S | Q1071L |
| NITMA1086 | C24784T | S | synonymous_variant |
| NITMA1086 | C26010T | ORF3a | synonymous_variant |
| NITMA1086 | A28055G | ORF8 | synonymous_variant |
| NITMA1086 | G28881A, G28882A | N | R203K |
| NITMA1086 | G28883C | N, ORF14 | G204R, G50N |
| NITMA1139 | C241T | Intergenic | upstream_gene_variant |
| NITMA1139 | C313T | ORF1ab | synonymous_variant |
| NITMA1139 | A4372G | ORF1ab | synonymous_variant |
| NITMA1139 | C3037T | ORF1ab | synonymous_variant |
| NITMA1139 | A5608G | ORF1ab | synonymous_variant |
| NITMA1139 | C5700A | ORF1ab | A1812D |
| NITMA1139 | C9693T | ORF1ab | A3143V |
| NITMA1139 | G9190T | ORF1ab | synonymous_variant |
| NITMA1139 | C14408T | ORF1ab | P314L |
| NITMA1139 | C16626T | ORF1ab | synonymous_variant |
| NITMA1139 | A18253G | ORF1ab | M15967V |
| NITMA1139 | C18555T | ORF1ab | synonymous_variant |
| NITMA1139 | C23230T | S | synonymous_variant |
| NITMA1139 | A23403G | S | D614G |
| NITMA1139 | G28881A, G28882A | N | R203K |
| NITMA1139 | G28883C | N, ORF14 | G204R, G50N |
a
Bold indicates the mutations leading to amino acid substitutions commonly observed in NITMA1086 and NITMA1139; italic indicates the other synonymous/intergenic variants commonly observed in NITMA1086 and NITMA1139.
b
SNP, single nucleotide polymorphism.