Table 3.

Genotype by Treatment Group Effects on the Likelihood of an Opioid-Positive UDS

		African Americans (n = 127)		European Americans (n = 327)
	[Interaction χ 2(1) = 0.07, P = .80]		[Interaction χ 2(1) = 17.35, P < .0001]
Genotype	Medication	Log odds of + UDS (SE)	LOR (95%CI)	Log odds of + UDS (SE)	LOR (95%CI)
CC	Placebo	2.30 (0.93)	1.83 (-0.02, 3.67)	1.04 (0.57)	1.08 (-0.11, 2.27)
CC	BUP-XR	0.48 (0.20)		-0.04 (0.21)
CT/TT	Placebo	1.67 (0.79)	1.52 (-0.12, 3.16)	2.25 (0.42)	2.86 (2.00, 3.71)
CT/TT	BUP-XR	0.15 (0.27)		-0.61 (0.12)

Abbreviations: BUP-XR, buprenorphine formulation; 95%CI = 95% confidence interval; LOR, log odds ratio; UDS, urine drug screen.