Table 3.

Nonlinear Regression Analysis of Dopamine D₂ Receptor Occupancy vs Dose

	Bmax (%)		D50 (mg/d)
	Estimate	95% CI	Estimate	95% CI
Tablets	75.3	60.0–90.7	2.18	−0.705–5.06
(n = 14)	100	Fixed	6.90	5.68–8.12
Transdermal patches	85.4	63.8–107	21.0	4.91–37.0
(n = 14)	100	Fixed	31.9	24.2–39.5

Abbreviations: B_max, maximum receptor occupancy expected; CI, confidence interval; D₅₀, dose at which 50% of B_max expected.