Table 1. Clinical data of the three Moroccan RP patients.
Patient | RP1.03 | RP2.03 | RP3.03 |
---|---|---|---|
Age |
17 |
13 |
23 |
Age at diagnosis |
12 |
9 |
21 |
First symptoms |
Night-blindness, difficulty to perceive side objects |
Night-blindness, difficulty to perceive side objects |
Night-blindness |
Consanguinity |
No |
First cousins |
Second cousins |
Visual field |
Not done |
Not done |
Severe impairment of the entire visual field with the persistence of tubular vision in both eyes |
ERG |
Flat traces |
Flat traces |
Flat traces |
Fundus imaging |
Not done |
Not done |
Grayish white aspect in the retinal periphery, slightly pale papilla on the temporal area and decreased retinal vessel size |
Auto- fluorescence imaging |
Not done |
Large hypo-fluorescence region in the central area and hyper-autofluorescence in the inferior area of the optic nerve head |
Discrete hyper-autofluorescence ring surrounding the macular area, large hypo-autofluorescence area in the peripheral retina and narrowed retinal vessels. |
Macular OCT | Not done | Cystoid macular edema, central thickness of 499µm in right eye and 512µm in left eye | Relative preservation of the foveal structure, disorganization of the ellipsoid zone in the perifovea in both eyes, and epiretinal membrane formation |
ERG: Electroretinogram; OCT: Optical coherence tomography.