Table 1. Bioavailability of SA-2 in the rat ocular tissue and fluids 1 h post dosing of 30 µl topical ocular eye drop of 1% w/v SA-2 NPs (n=12).
SA-2 NPs dose | Cornea | AH | VH | Retina | Choroid + Sclera |
---|---|---|---|---|---|
1% (w/v, 2.5 mM SA-2) | 2.6 pg/mg | 1.5 pg/mg | 9.4 pg/mg | 9.7 pg/mg | 3.37 pg/mg |