Table 2.
Hepcidin levels according to patient and tumor characteristics
| Variable | Hepcidin (ng/mL) | p-value | |
|---|---|---|---|
| Median | IQR | ||
| All patients | 16.3 | (11.9, 28.3) | – |
| Age (years) | |||
| < 50 | 13.6 | (10.6, 18.3) | < 0.01 |
| ≥ 50 | 23.8 | (15.8, 39.7) | |
| Body mass index (kg/m2) | |||
| ≤ 25 | 14.5 | (11.4, 23.2) | < 0.01 |
| 25–30 | 18.1 | (13.6, 28.3) | |
| > 30 | 21.8 | (12.9, 39.7) | |
| Menopausal status | |||
| Pre | 13.5 | (10.5, 17.0) | < 0.01 |
| Peri/post | 24.6 | (16.7, 39.9) | |
| Tumor grade | |||
| 3 | 16.8 | (11.8, 30.6) | 0.87 |
| 2 or 1 | 16.7 | (12.1, 28.0) | |
| T-stage | |||
| X, 2, 3 | 15.6 | (11.6, 30.3) | 0.96 |
| 1 | 16.7 | (12.1, 25.9) | |
| Nodal status | |||
| Positive | 16.9 | (11.8, 31.3) | 0.47 |
| Negative | 16.0 | (12.0, 25.9) | |
| Hormone receptor status | |||
| ER and/or PR positive | 15.3 | (11.3, 24.7) | 0.01 |
| ER and PR negative | 19.9 | (13.0, 33.7) | |
| Adjuvant chemotherapy | |||
| Yes | 14.7 | (11.3, 25.4) | 0.02 |
| No | 17.5 | (12.2, 30.5) | |
| Adjuvant radiation | |||
| Yes | 17.6 | (12.9, 30.4) | < 0.01 |
| No | 14.0 | (10.7, 21.5) | |
| Adjuvant hormone therapy | |||
| Yes | 20.5 | (13.5, 36.5) | < 0.01 |
| No | 14.6 | (11.1, 22.9) | |
| Primary surgery | |||
| Mastectomy | 12.8 | (10.4, 18.2) | < 0.01 |
| Lumpectomy | 17.7 | (12.9, 30.7) | |