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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Breast Cancer Res Treat. 2020 Sep 22;184(3):927–935. doi: 10.1007/s10549-020-05903-z

Table 2.

Hepcidin levels according to patient and tumor characteristics

Variable Hepcidin (ng/mL) p-value
Median IQR
All patients 16.3 (11.9, 28.3)
Age (years)
 < 50 13.6 (10.6, 18.3) < 0.01
 ≥ 50 23.8 (15.8, 39.7)
Body mass index (kg/m2)
 ≤ 25 14.5 (11.4, 23.2) < 0.01
 25–30 18.1 (13.6, 28.3)
 > 30 21.8 (12.9, 39.7)
Menopausal status
 Pre 13.5 (10.5, 17.0) < 0.01
 Peri/post 24.6 (16.7, 39.9)
Tumor grade
 3 16.8 (11.8, 30.6) 0.87
 2 or 1 16.7 (12.1, 28.0)
T-stage
 X, 2, 3 15.6 (11.6, 30.3) 0.96
 1 16.7 (12.1, 25.9)
Nodal status
 Positive 16.9 (11.8, 31.3) 0.47
 Negative 16.0 (12.0, 25.9)
Hormone receptor status
 ER and/or PR positive 15.3 (11.3, 24.7) 0.01
 ER and PR negative 19.9 (13.0, 33.7)
Adjuvant chemotherapy
 Yes 14.7 (11.3, 25.4) 0.02
 No 17.5 (12.2, 30.5)
Adjuvant radiation
 Yes 17.6 (12.9, 30.4) < 0.01
 No 14.0 (10.7, 21.5)
Adjuvant hormone therapy
 Yes 20.5 (13.5, 36.5) < 0.01
 No 14.6 (11.1, 22.9)
Primary surgery
 Mastectomy 12.8 (10.4, 18.2) < 0.01
 Lumpectomy 17.7 (12.9, 30.7)