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. 2021 Mar;110(3):1042–1053. doi: 10.1016/j.xphs.2020.11.039

Fig. 1.

Fig. 1

Developability assessment workflow for vaccine multi-dose formulation development as applied to evaluation of recombinant NRRV antigens (parent protein and sequence variants) produced in K. phaffii. Stage 1 physicochemical and immunochemical binding analyses are performed with antigens in solution, while Stage 2 stability studies are carried out with antigens in solution as well as bound to aluminum adjuvant.