Key Resource Table

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Human NOTCH1	Abcam	ab27526
Deposited Data
NALM16 WGS, RNAseq, Hi-C	EGA	EGAS00001004669
Table S1. List of publications as the sources of the pediatric cancer mutation and gene expression dataset
Table S2. Demographics information and DNA/RNA assay availability for every pediatric tumor used in the pediatric cancer dataset.
Table S3. List of pediatric cancer cell line sequencing datasets available in GenomePaint.
Experimental Models: Cell Lines
NALM6	DSMZ	ACC128
NALM16	DSMZ	ACC680
Oligonucleotides
Oligo sequences at MYC promoter for Capture-C: GATCAGAATCGATGCATTTTTTGTGCATGACCGCATTTCCAATAATAAAAGGGGAAAGAGGACCTGGAAAGGAATTAAACGTCCGGTTTGTCCGGGGAGGAAAGAGTTAACGGTTTTTTTC and CTAGGCATCGTTTTCCTCCTTATGCCTCTATCATTCCTCCCTATCTACACTAACATCCCACGCTCTGAACGCGCGCCCATTAATACCCTTCTTTCCTCCACTCTCCCTGGGACTCTTGATC	This paper	N/A
Software and Algorithms
GenomePaint	This paper	https://genomepaint.stjude.cloud//
CONSERTING	Chen et al. 2015	http://ftp.stjude.org/pub/software/conserting/CONSERTING_code.tgz
Cis-X	Liu et al. 2020	https://github.com/stjude/cis-x
VEP	McLaren et al. 2016	https://uswest.ensembl.org/info/docs/tools/vep/index.html