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. 2021 Feb 16;143(7):673–684. doi: 10.1161/CIRCULATIONAHA.120.052216

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© 2020 American Heart Association, Inc.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 1. — Change in endogenous FXa activity at 29 days. Values are expressed as percent inhibition (median) of baseline FXa at peak and trough with HDER and LDER. The difference in the change in endogenous FXa between men and women was tested using the nonparametric Wilcoxon rank-sum test. FXa indicates factor Xa; HDER, higher-dose edoxaban regimen; and LDER, lower-dose edoxaban regimen.