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. 2021 Feb 5;2021:7866720. doi: 10.1155/2021/7866720

Figure 2.

Figure 2

The Keap1/Nrf2 signaling pathway was significantly inhibited in the sensitive mice. (a, b) The protein levels of Keap1, Nrf2, HO-1, and NQO1 in the pancreatic islets of the mice were detected by Western blot analysis. (c) Pairwise correlation between blood glucose concentrations and protein levels of Keap1, Nrf2, HO-1, and NQO1. (d) Pairwise correlation between insulin levels and protein levels of Keap1, Nrf2, HO-1, and NQO1. The correlations were analyzed by using Pearson analysis. The data represent the mean ± SD (n = 5). ∗∗p < 0.01 and ∗∗∗p < 0.001 compared with the control group; ##p < 0.01 and ###p < 0.001 compared with the tolerant group.