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Nlrp3 deletion inhibited Nlrp3 inflammasome-related inflammatory cytokines. (a) The protein expression of heart IL-1β and IL-18 in the heart was determined by Western blotting and (b) the levels were normalized to β-actin in mice from the four groups. Serum IL-1β (c) and IL-18 (d) levels were measured via ELISA. All values are the means ± SEM (n = 6). ∗P < 0.05 versus the WT/vehicle control group; #P < 0.05 versus the WT/Ang II group.
