Table 5.
Univariate analysis and multivariate analysis for PIVKA-II.
| Parameters | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Age (≤ 50 vs. >50) | 0.351 (0.153-0.803) | 0.001 | 0.323 (0.120-0.864) | 0.024∗ |
| Sex (male vs. female) | 0.975 (0.221-4.303) | 0.930 | ||
| TBIL | 1.025 (0.280-3.753) | 0.971 | ||
| Tumor size | 7.070 (3.246-21.101) | < 0.001 | 4.280 (1.952-9.384) | 0.012∗ |
| Tumor differentiation (well vs. moderately/poorly) | 0.521 (0.135-2.013) | 0.344 | ||
| Tumor multiplicity (single vs. multiple) | 5.854 (1.742-19.621) | 0.004 | 1.209 (0.287-5.092) | 0.796 |
| BCLC staging | 2.890 (1.126-7.419) | 0.020 | 1.319 (0.468-3.717) | 0.600 |
| AFP | 2.156 (1.047-4.437) | 0.037 | 2.062 (0.874-4.487) | 0.069 |
| PVTT | 7.346 (2.579-20.921) | < 0.001 | 4.890 (1.361-38.169) | 0.020∗ |
PIVKA-II: prothrombin induced by vitamin K absence II; TBIL: total bilirubin; AFP: alpha-fetoprotein; CI: confidence interval; PVTT: portal vein tumor thrombus; ∗significant difference (P < 0.05).