Table 6.
Predictive factors of PVTT in hepatocellular carcinomas.
| Parameters | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Age (≤ 50 vs. > 50) | 0.443 (0.253-0.774) | 0.040 | 0.414 (0.214-0.799) | 0.009∗ |
| Sex (male vs. female) | 1.036 (0.449-2.388) | 0.934 | ||
| TBIL | 1.032 (1.006-1.058) | 0.016 | 1.025 (0.995-1.056) | 0.100 |
| Tumor size | 3.845 (1.370-10.789) | 0.011 | 2.515 (0.258-24.55) | 0.428 |
| Tumor differentiation (well vs. moderately/poorly) | 1.025 (0.280-3.753) | 0.971 | ||
| Tumor multiplicity (single vs. multiple) | 3.065 (1.745-5.381) | < 0.001 | 2.118 (1.097-4.089) | 0.025∗ |
| BCLC staging | 6.053 (1.522-24.071) | 0.011 | 0.211 (0.012-3.824) | 0.292 |
| AFP | 2.641 (1.312-5.318) | 0.007 | 1.536 (0.710-3.323) | 0.276 |
| PIVKA-II | 7.346 (2.579-20.921) | < 0.001 | 4.890 (1.361-38.169) | 0.020∗ |
TBIL: total bilirubin; AFP: alpha-fetoprotein; PIVKA-II: protein induced by vitamin K absence or antagonist-II; CI: confidence interval; PVTT: portal vein tumor thrombus; ∗Significant difference (P < 0.05).