Amino acid	Frequency of AA in proteome (%)	Total # of AAs	Water molecules/AA	Total # of water molecules	Total # of water as percent of water in E. coli (%)
Ala	9.52	1.00 × 108	6.5	6.50 × 108	2.78
Cys	1.16	1.22 × 107	7.5	9.15 × 107	0.39
Asp	5.15	5.41 × 107	19.5	1.05 × 109	4.51
Glu	5.76	6.05 × 107	12.5	7.56 × 108	3.23
Phe	3.89	4.08 × 107	15.5	6.32 × 108	2.70
Gly	7.37	7.74 × 107	10.5	8.13 × 108	3.47
His	2.27	2.38 × 107	15	3.57 × 108	1.53
Ile	6.01	6.31 × 107	34	2.15 × 109	9.17
Lys	4.41	4.63 × 107	36	1.67 × 109	7.12
Leu	10.67	1.12 × 108	16	1.79 × 109	7.66
Met	2.82	2.96 × 107	26.5	7.84 × 108	3.35
Asn	3.95	4.15 × 107	21.5	8.92 × 108	3.81
Pro	4.43	4.65 × 107	15.5	7.21 × 108	3.08
Gln	4.44	4.66 × 107	12.5	5.83 × 108	2.49
Arg	5.51	5.79 × 107	19.5	1.13 × 109	4.83
Ser	5.8	6.09 × 107	6.5	3.96 × 108	1.69
Thr	5.4	5.67 × 107	23.5	1.33 × 109	5.69
Val	7.07	7.42 × 107	12	8.90 × 108	3.81
Trp	1.53	1.61 × 107	18.5	2.98 × 108	1.27
Tyr	2.85	2.99 × 107	14.5	4.34 × 108	1.85
Sum		1.05 × 109		1.74 × 1010	74.4