Table 3.
Patient | Muscle enzymes | Cardiac testing | Kidney function | Respiratory function | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Creatine kinase (U/L)a | Aldolase (U/L)b | Troponin-T (ng/ml)c | NTproBNP (pg/ml)d | QT interval duration (ms)e | Ejection fraction (%) | Increased wall thickness (Y/N) | Restrictive vs. dilated CMP | CQ/HCQ CMP | Creatinine (mg/dl)f | Vital capacity (%)g | |
1 | 110 | 6.8 | 447 | 66 | N | No | 1.1 | 89 | |||
2 | 557 | ||||||||||
3 | 244 | 5.1 | 0.12 | 2,896 | 457 | 72 | Y | R | Most likely | 1.2 | 89 |
4 | 651 | 8.5 | <0.01 | 468 | 70 | N | No | 0.9 | 123 | ||
5 | 125 | 6.4 | 448 | 65 | N | No | 0.8 | 82 | |||
6 | 1,199 | 35.7 | 0.76 | 8,812 | 498 | 32 | N | D | No | 1 | 33 |
7 | 149 | 4.1 | 447 | 50 | N | R | Possible | 0.5 | 47 | ||
8 | 403 | 493 | 70 | Y | R | Most likely | 0.9 | 68 | |||
9 | 560 | 0.09 | 4,786 | 432 | 49 | N | R | No | 0.8 | 58 | |
10 | 337 | 6.4 | 1.1 | 79 | |||||||
11 | 386 | 0.17 | 4,277 | 560 | 69 | Y | R | Most likely | 0.9 | ||
12 | 135 | 6.9 | 0.13 | 7,255 | 476 | 27 | N | R | Possible | 2.8 | 61 |
13 | 302 | 0.36 | 25,681 | 634 | 33 | Y | R | Definite | 1.1 |
Abnormal values are in bold.
Normal range:
38–176 U/L, except patients #2 and #5: 52–336 U/L;
<7.7 U/L;
<0.01 ng/ml;
≤ 206 pg/ml;
400–440 ms.
Females: 0.59–1.04 mg/dl and males 0.74–1.35 mg/dl.
≥70% of predicted.
CQ, chloroquine; HCQ, hydroxychloroquine; CMP, cardiomyopathy; D, dilated cardiomyopathy; NTproBNP, N-terminal pro-brain natriuretic peptide; R, restrictive cardiomyopathy.