Table 3.

Multiple regression analysis for asymmetry in the visual and semiquantitative analysis based on total CERAD score.

Region	Independent variable Asymmetry β (p)	Covariates Age β (p)	Gender β (p)	YoE β (p)	Total burden FDG-PET β (p)
Visual
Hemispheres	−0.288 (<0.001)	−0.168 (0.020)	0.177 (0.017)	0.220 (0.002)	0.435 (<0.001)
Parietal lobe	−0.276 (<0.001)	−0.163 (0.024)	0.168 (0.023)	0.211 (0.004)	0.440 (<0.001)
Temporal lobe	−0.262 (<0.001)	−0.181 (0.013)	0.161 (0.029)	0.231 (0.002)	0.429 (<0.001)
Posterior cingulate cortex	−0.219 (0.003)	−0.149 (0.045)	0.158 (0.037)	0.238 (0.001)	0.414 (<0.001)
Semiquantitative
Hemispheres	−0.451 (<0.001)	−0.140 (0.049)	0.131 (0.071)	0.185 (0.012)	0.442 (<0.001)
Parietal lobe	−0.419 (<0.001)	−0.125 (0.081)	0.110 (0.129)	0.191 (0.010)	0.414 (<0.001)
Temporal lobe	−0.445 (<0.001)	−0.143 (0.046)	0.139 (0.057)	0.191 (0.010)	0.444 (<0.001)
Posterior cingulate cortex	−0.168 (0.035)	−0.089 (0.251)	0.069 (0.376)	0.269 (0.001)	0.303 (<0.001)

CERAD, Consortium to Establish a Registry for Alzheimer’s disease. FDG-PET, F-18-fluorodeoxyglucose positron emission tomography.