TABLE 1.

COMSTAT analysis of architectural parameters of Candida tropicalis NCPF 3111 biofilms.

	Biofilms 1		Biofilms 2
	Untreated	AmB SMIC80	Untreated	AmB SMIC80
Bio-volume (μm3 μm–2)	2.69 ± 0.23	0.59 ± 0.05*	1.43 ± 0.03#	0.55 ± 0.02*
Average micro-colony volume (μm3)	3.63 ± 0.28	0.75 ± 0.021*	1.30 ± 0.06#	0.65 ± 0.02*#
Surface to bio-volume ratio (μm2 μm–3)	7.21 ± 0.27	6.30 ± 0.29*	5.62 ± 0.09#	7.55 ± 0.18*#
Roughness coefficient (Ra*)	1.00 ± 0.01	1.32 ± 0.02*	1.00 ± 0.01	1.31 ± 0.02*
Average diffusion distance (μm)	0.07 ± 0.00	0.21 ± 0.01*	0.05 ± 0.00#	0.18 ± 0.01*
Surface coverage (%)	96.57 ± 5.30	35.03 ± 1.70*	98.74 ± 1.63	43.89 ± 1.50*#

All experiments were performed in triplicate, and numerical data are presented as means ± standard deviation. *Denotes statistical significance at p < 0.01 for comparisons with untreated biofilms. ^#Denotes statistical significance at p < 0.01 for comparisons between AmB-treated biofilms (B1 and B2).