. 2021 Feb 15;7:15. doi: 10.1038/s41531-021-00159-w

Table 3.

Correlation analysis of HCBs grade with variables in MSA patients.

Variables	Overall	(n = 81)	MSA-C	(n = 50)	MSA-P	(n = 31)
Variables	r	p^†	r	p^†	r	p^†
Autonomic failure
Orthostatic hypotension	−0.085	0.453	−0.061	0.675	−0.179	0.335
Urinary incontinence	0.119	0.288	0.139	0.337	0.089	0.636
Incomplete bladder empty	0.043	0.706	−0.026	0.859	0.195	0.294
Constipation	0.180	0.108	0.177	0.220	0.186	0.316
Cerebellar dysfunction
Gait ataxia	0.177	0.114	0.021	0.885	0.314	0.086
Limb ataxia	0.308	0.005	0.183	0.203	0.442	0.013
Cerebellar dysarthria	0.261	0.019	0.319	0.024	0.091	0.627
Nystagmus	−0.135	0.230	−0.194	0.178	…	…
Parkinsonism
Bradykinesia	−0.041	0.719	0.084	0.563	−0.219	0.236
Rigidity	−0.116	0.304	−0.043	0.766	−0.183	0.325
Postural instability	−0.161	0.152	−0.163	0.258	−0.123	0.509
Resting tremor	−0.059	0.604	0.110	0.447	−0.277	0.132
Corticospinal dysfunction
Babinski sign	0.174	0.120	0.196	0.173	0.166	0.373
Atypical symptoms
Dementia	−0.081	0.471	−0.110	0.446	−0.022	0.906
Neurological Scores
SARA	0.594	<0.001	0.788	<0.001	0.326	0.073
UMSARS-IV	0.560	<0.001	0.794	<0.001	0.154	0.408
Imaging features
Atrophy of pons	−0.311	0.005	−0.271	0.057	−0.357	0.048
Atrophy of MCP	−0.411	<0.001	−0.383	0.006	−0.434	0.015
Disease duration	0.179	0.093	0.109	0.520	0.376	0.037
Age on symptom onset	−0.061	0.587	−0.582	0.573	−0.132	0.479

^†Based on Spearman test, significance level of 0.05 (two-tailed).

UMSARS Unified Multiple System Atrophy Rating Scale, MSA-C multiple system atrophy (cerebellar subtype), MSA-P multiple system atrophy (parkinsonism subtype), MCP middle cerebellar peduncles.