. 2021 Feb 15;7:15. doi: 10.1038/s41531-021-00159-w

Table 4.

Relationship between HCBs and severity of ataxia as assessed by score of sums and each item of SARA.

Variables	Overall	(n = 81)	p^†	MSA-C	(n = 50)	p^†	MSA-P	(n = 31)	p^†
Variables	r²	Adjusted r²	p^†	r²	Adjusted r²	p^†	r²	Adjusted r²	p^†
SARA	0.451	0.339	<0.001	0.634	0.573	<0.001	0.392	0.206	0.148
Gait	0.510	0.432	<0.001	0.705	0.619	<0.001	0.444	0.166	0.808
Stance	0.511	0.449	<0.001	0.759	0.705	<0.001	0.485	0.298	0.335
Sitting	0.462	0.410	<0.001	0.634	0.573	<0.001	0.394	0.290	0.748
Speech disturbance	0.304	0.205	0.221	0.363	0.220	0.081	0.389	0.167	0.887
Finger–finger test	0.386	0.308	0.005	0.467	0.347	0.005	0.409	0.195	0.775
Nose–finger test	0.454	0.393	<0.001	0.603	0.526	<0.001	0.373	0.145	0.953
Fast alternating hand movements	0.383	0.314	0.002	0.502	0.404	0.001	0.389	0.167	0.887
Heel–shin slide	0.397	0.330	0.001	0.554	0.467	<0.001	0.410	0.195	0.772

^†Based on General Linear Model with univariate analysis, atrophy of pons, atrophy of MCP and disease duration were analyzed as covariates. significance level of 0.05 (two-tailed).

UMSARS Unified Multiple System Atrophy Rating Scale, MSA-C multiple system atrophy (cerebellar subtype), MSA-P multiple system atrophy (parkinsonism subtype).