Table 1.
Correlation of UBE2S expression and clinicopathologic features in patients with hepatocellular carcinoma
| Clinicopathological variables | UBE2S expression | P value | Nuclear UBE2S expression | P value | ||
|---|---|---|---|---|---|---|
| High (n = 57) | Low (n = 23) | Positive (n = 41) | Negative (n = 39) | |||
| Gender | ||||||
| Male | 47 | 22 | 0.233 | 33 | 36 | 0.125 |
| Female | 10 | 1 | 8 | 3 | ||
| Age | ||||||
| <50 years | 22 | 10 | 0.687 | 14 | 18 | 0.273 |
| ≥50 years | 35 | 13 | 27 | 21 | ||
| HBsAg | ||||||
| Positive | 49 | 21 | 0.779 | 35 | 35 | 0.800 |
| Negative | 8 | 2 | 6 | 4 | ||
| Serum AFP | ||||||
| <20 (ng/ml) | 17 | 9 | 0.421 | 13 | 13 | 0.877 |
| ≥20 (ng/ml) | 40 | 14 | 28 | 26 | ||
| Tumor number | ||||||
| Single | 37 | 20 | 0.049 | 25 | 32 | 0.037 |
| Multiple | 20 | 3 | 16 | 7 | ||
| Tumor size | ||||||
| <5 cm | 17 | 15 | 0.003 | 10 | 22 | 0.003 |
| ≥5 cm | 40 | 8 | 31 | 17 | ||
| TNM stage | ||||||
| 1 | 32 | 19 | 0.026 | 23 | 28 | 0.144 |
| 2–4 | 25 | 4 | 18 | 11 | ||
| Tumor differentiation | ||||||
| I–II | 22 | 10 | 0.687 | 16 | 16 | 0.855 |
| III–IV | 35 | 13 | 25 | 23 | ||
HbsAg hepatitis B virus surface antigen, AFP alpha-fetoprotein, TNM tumor-node metastasis. Values in bold indicate statistically significant differences