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. 2021 Feb 15;11:3828. doi: 10.1038/s41598-021-83270-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in Optical Absorption (µ_a) and Scattering (µ_s′) Properties during Asphyxia (left) and CPR (right): Shown are the median (thick line) and interquartile range (shaded) of the measured changes during asphyxia (all subjects, black) and during CPR (ROSC, blue; No-ROSC, red), expressed as a percentage (%) of baseline. Significant increases in µ_a at 690, 725, and 785 nm and µ_s′ at 785 nm were observed at the end of asphyxia. In the 10th minute of CPR, the change in µ_a at 785 and 830 nm from baseline was significantly greater in ROSC versus No-ROSC subjects, however change in µ_s′ at 785 nm was significantly greater in No-ROSC versus ROSC subjects (*, p < 0.05; **, p < 0.01; ***, p < 0.001).