Table 1.
Baseline n = 48 |
Asphyxia, End (Δ Baseline) |
p value† | CPR, 10 min (Δ Baseline) | |||
---|---|---|---|---|---|---|
ROSC n = 37 |
No-ROSC n = 11 | p value‡ | ||||
Optical absorption coefficient µa (λ), (1/cm) | ||||||
µa (690 nm) |
0.16 [0.14, 0.19] |
+ 0.07 [0.05, 0.09] |
< 0.001 |
+ 0.05 [0.03, 0.06] |
+ 0.03 [0.02, 0.05] |
0.294 |
µa (725 nm) |
0.14 [0.12, 0.15] |
+ 0.04 [0.03, 0.05] |
< 0.001 |
+ 0.03 [0.02, 0.04] |
+ 0.02 [0.00, 0.03] |
0.105 |
µa (785 nm) |
0.14 [0.13, 0.15] |
+ 0.02 [0.01, 0.03] |
< 0.001 |
+ 0.01 [0.01, 0.02] |
− 0.02 [− 0.02, 0.00] |
0.011 |
µa (830 nm) |
0.15 [0.13, 0.16] |
+ 0.00 [− 0.01, 0.00] |
0.061 |
+ 0.00 [− 0.00, 0.01] |
− 0.01 [− 0.04, − 0.00] |
0.001 |
Optical reduced scattering coefficient µs′ (λ), (1/cm) | ||||||
µs′ (690 nm) |
10.9 [9.9, 11.8] |
+ 0.0 [− 0.4, 0.4] |
0.759 |
− 0.0 [− 0.6, 0.4] |
+ 0.3 [− 0.4, 0.6] |
0.233 |
µs′ (725 nm) |
10.2 [9.2, 10.9] |
+ 0.1 [− 0.2, 0.2] |
0.320 |
− 0.2 [− 0.5, 0.4] |
+ 0.1 [− 0.2, 0.4] |
0.204 |
µs′ (785 nm) |
9.3 [8.3, 10.2] |
+ 0.1 [− 0.1, 0.5] |
0.024 |
− 0.1 [− 0.4, 0.1] |
+ 0.5 [0.3, 0.9] |
0.005 |
µs′ (830 nm) |
8.7 [7.9, 9.4] |
+ 0.0 [− 0.1, 0.2] |
0.339 |
− 0.2 [− 0.5, 0.2] |
+ 0.1 [0.0, 0.4] |
0.077 |
Mie scattering model fit parameters, µs′(λ) = a*(λ/500 nm)^b | ||||||
a, (1/cm) |
15.4 [12.1, 18.8] |
+ 0.2 [− 1.3, 1.5] |
0.604 |
− 0.44 [− 1.89, 1.47] |
+ 0.59 [− 1.23, 1.63] |
0.691 |
b |
1.1 [0.7, 1.6] |
+ 0.0 [− 0.2, 0.2] |
0.837 |
+ 0.04 [− 0.24, 0.30] |
− 0.02 [− 0.20, 0.16] |
0.691 |
Goodness-of-fit (adjusted R2) |
0.82 [0.54, 0.94] |
− 0.02 [− 0.10, 0.05] |
0.142 |
− 0.03 [− 0.22, 0.05] |
+ 0.08 [0.01, 0.17] |
0.026 |
Values summarized as median [IQR].
†p value from Wilcoxon signed-rank test.
‡p value from Wilcoxon rank-sum test comparing ROSC and No-ROSC groups.
λ, wavelength; Δ Baseline, change from Baseline; ROSC, return of spontaneous circulation; a, fitted reduced scattering coefficient at λ = 500 nm; b, scattering power.