Figure 8.

Expression of transcription factors Eomes and T-bet in the PD-1 positive CD8⁺ T cells during the acute and memory stage. Upon i.c. inoculation with AdIi-GP brains were extracted day 11 - and 60 post i.c. Intracellular expression of the transcription factors Eomes and T-bet were analyzed for both total CD8⁺ - and antigen specific (tetramer⁺) CD8⁺ T cells. The expressions were shown in representative histograms of 5 mice from each time point. FMOs were included to indicate background. Results are representative of 3 experiments.