Table 2.
Microstructural evaluations of subchondral trabeculae and cartilage damage in the OA, OP-OA, and NC groups.
| OA | OP-OA | NC |
p-Value OA vs. OP-OA |
|
|---|---|---|---|---|
| BV/TV (%) | 33.16 ± 11.39a | 22.54 ± 7.50 | 23.32 ± 5.07 | 0.006**# |
| pBV/TV (%) | 25.28 ± 7.58 | 18.35 ± 6.89 | 18.87 ± 5.63 | 0.021*# |
| rBV/TV (%) | 7.88 ± 4.57a | 4.19 ± 2.22 | 4.45 ± 2.05 | 0.010*# |
| pBV/BV (%) | 77.56 ± 6.55 | 79.59 ± 12.56 | 80.07 ± 10.45 | 0.634 |
| rBV/BV (%) | 22.44 ± 6.55 | 20.41 ± 12.56 | 19.93 ± 10.45 | 0.643 |
| pTb.N (1/mm) | 3.18 ± 0.27a | 2.84 ± 0.36b | 2.47 ± 0.55 | 0.044*# |
| rTb.N (1/mm) | 2.91 ± 0.41a | 2.48 ± 0.48 | 2.09 ± 0.37 | 0.021*# |
| pTb.Th (mm) | 0.14 ± 0.01 | 0.13 ± 0.01b | 0.15 ± 0.02 | 0.117 |
| rTb.Th (mm) | 0.09 ± 0.01a | 0.09 ± 0.00b | 0.12 ± 0.03 | 0.940 |
| pTb.S (mm2) | 0.05 ± 0.00a | 0.06 ± 0.01b | 0.09 ± 0.03 | 0.627 |
| rTb.l (mm) | 0.34 ± 0.02a | 0.33 ± 0.01b | 0.41 ± 0.08 | 0.561 |
| R-R Junc.D (1/mm3) | 7.89 ± 4.56a | 5.53 ± 4.23 | 2.99 ± 1.76 | 0.158 |
| R-P Junc.D (1/mm3) | 50.19 ± 23.33a | 28.36 ± 16.57 | 16.21 ± 12.02 | 0.008**# |
| P-P Junc.D (1/mm3) | 34.59 ± 11.08a | 23.55 ± 11.18 | 14.81 ± 11.45 | 0.023*# |
| OARSI score | 14.45 ± 3.95a | 17.46 ± 3.10b | 3.43 ± 1.62 | 0.030*# |
Symbol “*” indicates comparisons between the OA and OP-OA groups.
*
Indicates p < 0.05.
**
Indicates p < 0.01.
#
Indicates that p-value remained significant after adjustment for age, height and weight.
a
p < 0.05 between OA and NC group.
b
p < 0.05 between OP and NC group and remained significant after adjustment for height and weight.